
年彬彬,副教授,硕士生导师,江苏省“双创计划”高层次人才科技副总,江苏省对外科学技术促进会科技青年智库专家,主要从事基于多重计算机辅助技术的功能脂质专用酶挖掘、理性设计、高效生物催化策略开发、酶-催化环境适配机制解析等方面的教学与科研工作。相关研究成果,以第一/通讯作者在ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, Advanced materials,ACS catalysis等国际期刊发表 SCI 论文 50 余篇,申请/授权国内外发明专利10余件,出版十四五规划教材2部,作为主要参与人员获2024年度中国轻工业联合会科学技术进步奖二等奖1项。
Ø 代表性论文
1. Chong, W., Qi, Y., Ji, L., Zhang, Z., Lu, Z., Nian, B.* and Hu, Y.*, 2023. Computer-aided tunnel engineering: a promising strategy for improving lipase applications in esterification reactions. ACS Catalysis, 14(1), pp.67-83. (中科院一区,IF:13.1)
2. Qi, Y., Chen, M., Jin, T., Chong, W., Zhang, Z., Nian, B.* and Hu, Y.*, 2024. Computer-aided engineering of lipases solvent tolerance enhanced their applications in sugar esters synthesis: State of the art. Trends in Food Science & Technology, 144, p.104323. (中科院一区,IF:15.4)
3. Ji, L., Du, J., Zhang, W., Lu, Z., Nian, B.* and Hu, Y.*, 2025. Dual role of ionic liquid modified β-Cyclodextrin in dynamic conformational regulation and substrate enrichment for improved lipase immobilization. Carbohydrate Polymers, p.123786. (中科院一区,IF:12.5)
4. Nian, B. and Hu, Y., 2022. Anionic H-bonds improve the disorganization of starch in metal chloride hydrate-natural deep eutectic solvents. Carbohydrate Polymers, 298, p.120150. (中科院一区,IF:12.5)
5. Xie, M., Du, J., Jia, M., Nie, X., Zhang, X., Hu, Y.* and Nian, B.*, 2025. Computer-Aided Techniques in the Engineering of Enzyme Binding Pockets: New Perspectives and Frontiers. Journal of Agricultural and Food Chemistry, 73(33), pp.20600-20615. (中科院一区,IF:6.2)
6. Qi, Y., Zhang, Z., Liu, Y., Liang, C., Chong, W., Nian, B.* and Hu, Y.*, 2024. Lipase Substrate Anchoring Dynamics Guided the Rational Design of Novel Deep Eutectic Solvents for Glucose Ester Synthesis. Journal of Agricultural and Food Chemistry, 72(42), pp.23401-23410. (中科院一区,IF:6.2)
7. Zhang, Z., Zhang, Y., Liu, Y., Liang, C., Nian, B.* and Hu, Y.*, 2024. Amino-Alkyl Group Dual-Functional Modification Synergistically Regulated Lipase-Carrier Interactions and Enhanced Phytosterol Ester Synthesis Efficiency. Journal of Agricultural and Food Chemistry, 72(42), pp.23345-23354. (中科院一区,IF:6.2)
8. Han, Y.#, Fang, H., Nie, X., Zhang, X., Lu, Z., Nian, B.#, Hu, Y.* and Cheng, W.*, 2025. Potential applications of lipases rational design in the synthesis of medium-and long-chain triglycerides: Current advances and perspectives. Food Chemistry, p.146049.(中科院一区,IF:9.8)
9. Nian, B., Xu, Y.J. and Liu, Y., 2021. Molecular dynamics simulation for mechanism revelation of the safety and nutrition of lipids and derivatives in food: State of the art. Food Research International, 145, p.110399. (中科院一区,IF:8.0)
10. Zhao, J., Qi, Y., Chen, Y., Zhang, M., An, Z., Wang, W., Nian, B.*, Li, Y., Han, S*. and Zhang, L.*, 2025. High‐Performance Zinc Halogen Aqueous Battery Exploiting [BrCl2]− Storage in Ketjenblack by Reconstructing Electrolyte Structure. Angewandte Chemie, 137(17), p.e202421905. (中科院一区,IF:17.0)
Ø 代表性项目
(1) 国家重点研发计划项目子课题(2021YFC2103802),2021/12-2025/11
(2) 国家自然科学基金青年项目(32402026),2025.01-2027.12
(3) 黑龙江省博后面上项目(BS082),2025.01-2027.01
(4) 江苏省高等学校基础科学(自然科学)面上项目(重点),2024.12-2026.12
(5) 企业委托横向项目,功能脂质绿色制备,2024.10-2026.10
联系方式:bbnian@njetch.edu.cn