朱亦龙,副教授,硕士生导师。
2017年在南京工业大学获得工学博士学位;2017年12月至2018年12月在美国Texas Tech University从事博士后研究;2019年至今在南京工业大学药学院从事教学科研工作。主要从事绿色有机合成方法学、新药研发与合成工艺开发等相关研究工作。作为项目负责人主持国家自然科学基金青年项目、江苏省自然科学基金青年项目等;以通讯或第一作者在Chem. Commun.、Org. Lett.、Adv. Synth. Catal.、Org. Chem. Front.、J. Org. Chem.等发表论文二十余篇。
研究方向:
1. 绿色有机合成方法学
2. 药物合成新方法及新药研究与开发
科研项目:
2019.01-2021.12 国家自然科学基金青年项目(项目号:21801130),主持/完成
2018.07-2021.06 江苏省自然科学基金青年项目(项目号:BK20180689),主持/完成
2019.09-2020.02 新型端氰基键合剂中间体工艺放大研究(技术服务,横向),主要参与/完成
2019.06-2020.03 一种有机凝胶剂分子的中试工艺流程开发(技术服务,横向),主要参与/完成
2018.04-2028.04 NPFA等五个原料药的绿色合成工艺研发(技术服务,横向),主要参与/在研
代表性研究成果(近五年):
第一作者或通讯作者*发表的期刊论文
(1) Yu-Lin Zhai, Hui Zhou, Qing-Quan Liu, Bo-Rong Leng, Zixian Zhang, Jia-Zhuo Li, De-Cai Wang* and Yi-Long Zhu*. Photocatalytic Markovnikov-type addition and cyclization of terminal alkynes leading to 4-sulfonyl quinoline-2(1H)-ones. Chem. Commun., 2022, 58, 5112-5115.
(2) Luan-Ying Li, Bo-Rong Leng, Jia-Zhuo Li, Qing-Quan Liu, Jianguang Yu,* Ping Wei, De-Cai Wang* and Yi-Long Zhu*. Palladium-catalyzed regioselective hydrosulfonylation of allenes with sulfinic acids. RSC Adv., 2022,12, 8443-8448.
(3) Chi-Fan Zhu, Jie Zhang, Yi-Long Zhu,* Wen-Juan Hao, Shu-Jiang Tu, De-Cai Wang* and Bo Jiang*. A photoinduced arene–alkyne [3 + 2] cycloaddition cascade of 1-alkynylnaphthalen-2-ols for tunable synthesis of skeletally diverse bridged hexacycles. Org. Chem. Front., 2021,8, 1952-1958.
(4) Chi-Fan Zhu, Cong-Hui Gao, Wen-Juan Hao, Yi-Long Zhu,* Shu-Jiang Tu, De-Cai Wang* and Bo Jiang*. Synthesis of C3-alkylated benzofurans via palladium-catalyzed regiocontrolled hydro-furanization of unactivated alkenes. Org. Chem. Front., 2021, 8, 127-132.
(5) Hong-Ming Huang, Xu-Yan Wu, Bo-Rong Leng, Yi-Long Zhu,* Xin-Chao Meng, Yu Hong, Bo Jiang* and De-Cai Wang*. Cu(II)-Catalyzed formal [4+2] cycloaddition between quinone methides (QMs) and electron-poor 3-vinylindoles. Org. Chem. Front., 2020, 7, 414-419.
(6) Yi-Long Zhu, Chi-Fan Zhu, Peng Zhou, Wen-Juan Hao*, De-Cai Wang, Shu-Jiang Tu*, and Bo Jiang*. Pd(II)-Catalyzed Carbonyl-Directing Activation of Alkenes: Selective Fluorosulfonylation and Aminosulfonylation of 1,7-Enynes. J. Org. Chem. 2018, 83, 9641-9653.
(7) Min-Hua Huang, Chi-Fan Zhu, Chun-Lan He, Yi-Long Zhu*, Wen-Juan Hao, De-Cai Wang*, Shu-Jiang Tu, Bo Jiang*. Visible-light-induced methylsulfonylation/bicyclization of C(sp3) tethered 1,7-enynes using DMSO/H2O system. Org. Chem. Front. 2018, 5, 1643-1650.
(8) Min-Hua Huang, Yi-Long Zhu (Co-first author), Wen-Juan Hao, Ai-Fang Wang, De-Cai Wang*, Feng Liu, Ping Wei, Shu-Jiang Tu*, Bo Jiang*. Visible-Light Photocatalytic Bicyclization of 1,7-Enynes toward Functionalized Sulfone-Containing Benzo[a]fluoren-5-ones. Adv. Synth. Catal. 2017, 359, 2229-2234.
(9) Yi-Long Zhu, Ai-Fang Wang, Jian-Yu Du, Bo-Rong Leng, Shu-Jiang Tu*, De-Cai Wang, Ping Wei*, Wen-Juan Hao and Bo Jiang*. Ag-Catalyzed difluorohydration of β-alkynyl ketones for diastereoselective synthesis of 1,5-dicarbonyl compounds. Chem. Commun. 2017, 53, 6397-6400. (Inside Front Cover)
E-mail: zhuyilong_88@njtech.edu.cn