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任丽莉
阅读次数:     发布时间:2017-04-19

任丽莉,教授,硕士生导师,药剂学教研室主任

美国斯坦福大学访问学者。研究领域为药物新剂型与新技术、药物组合性递送策略以及中药活性成分的分离和纯化。江苏省药物研究与开发协会会员、江苏省高新技术企业评审专家,江苏省中青年科技评审专家。近年来,主持和参与国家和省级多项科研项目,以及多项企业横向合作开发项目。发表各类学术论文30余篇,其中,SCI论文20余篇,曾被NAT COMMUNPNAS等杂志收录。

工作经历:

2004.9-2011.6 南京工业大学生工学院,讲师

2011.7-2020.6 南京工业大学药学院,副教授

2016.9-2017.9 美国斯坦福大学,访问学者

2020.7至今,南京工业大学药学院,教授

科研项目:

1.江苏省社会发展重点研发计划,基于生物智能可降解型材料的肿瘤精准治疗,2019.7-2022.12,主持;

2.江苏省教育厅中外合作办学平台联合科研项目,基于肿瘤精准治疗的生物可降解载体材料的合作开发,2019.7-2020.6,主持;

3.江苏省苏北专项,银杏叶聚戊烯醇分离提纯技术研发及产业化,2016.1-2018.12,主持;

4.国家重大专项重大新药创制项目,植物源雌激素样作用药物-益母草碱的临床前研究,2017.1-2020.12,参加。

科研奖励:

1. 难溶性药物/功能性食品高效增溶的关键性技术开发与应用,中国商业联合会科技进步二等奖,排名第一

2. 增溶技术在几类功能性食品/难溶性药物生产中的应用,江苏省轻工业科学进步一等奖,排名第一

部分发表论文:

1. Ren L, He G, Zhou Y, Dai J, Miao W, Ouyang C, Liu J and Chen G*. A hydrogel based on nanocellulose/polydopamine/gelatin used for the treatment of MRSA infected wounds with broad-spectrum antibacterial and antioxidant properties and tissue suitability[J]. Biomaterials Science, 2022, 10: 3174-3187.

2. Yin J, Ouyang C, Shen S, Zhou Y, He G, Zhang H, Zhou K, Chen G * and Ren L *. A Redox-Activatable and Targeted Photosensitizing Agent to Deliver Doxorubicin for Combining Chemotherapy and Photodynamic Therapy[J]. Molecular Pharmaceutics, 2022, 19: 2441-2455.

3. Chen G, Zhou Y, Dai J, Yan S, Miao W, Ren L*. Calcium alginate/PNIPAAm hydrogel with body temperature response and great biocompatibility: Application as burn wound dressing[J]. International Journal of Biological Macromolecules, 2022, 216: 686-697.

4. Li Y, Nie J, Dai J, Yin J, Huang B, Liu J, Chen G* and Ren L*. pH/Redox dual-responsive drug delivery system with on-demand RGD exposure for photochemotherapy of tumors[J]. International Journal of Nanomedicine, 2022, 23(17): 5621-5639.

5. Ren L*, Lirong Qiu, Binbin Huang, Jun Yin, Yaning Li, Xiaolong Yang and Guoguang Chen. Preparation and Characterization of Anti-Cancer Crystal Drugs Based on Erythrocyte Membrane Nanoplatform[J]. Nanomaterials, 2021, 11: 2513-2525.

6. Ren L*, Nie J, Wei J, Li Y, Yin J, Yang L & Chen G*. RGD-targeted redox responsive nano micelle: co-loading docetaxel and indocyanine green to treat the tumor[J]. Drug Delivery, 2021, 28(1): 2024-2032.

7. Ding, S., Song, Y., Brulois, K. F., Pan, J., Co, J. Y., Ren, L., Feng, N., Yasukawa, L. L., Sánchez-Tacuba, L., Wosen, J. E., Mellins, E. D., Monack, D. M., Amieva, M. R., Kuo, C. J., Butcher, E. C., Greenberg, H.B. g. Retinoic Acid and Lymphotoxin Signaling Promote Differentiation of Human Intestinal M Cells[J]. Gastroenterology, 2020, 159(01): 214-226.

8.  Ren L*, Ding S*, Song Y*, Li B*, Co J, Ramanathan M, Amieva MR, Khavari PA, and Greenberg HB. Profiling of rotavirus 3 UTR-binding proteins reveals the ATP synthase subunit ATP5B as a host factor that supports late-stage virus replication[J]. Journal of Biological Chemistry, 2019, 294(15): 5993-6006.

9. Ding S, Diep J, Feng N, Ren L, Li B, Ooi YS, Wang X, Brulois KF, Li X, Kuo CJ, Solomon DA, Carette JE, and Greenberg HB. STAG2deficiency induces IFN responses via cGAS-STING pathway and restricts virus infection[J]. Nature Communications, 2018, 9: 1485.

10. Li B, Ding S, Feng N, Mooney N, Ooi Y, Ren L, Diep J, Kelly M, Yasukawa L, Patton J, Yamazaki H, Shirao T, Jackson P, and Greenberg HB. Drebrin restricts rotavirus entry by inhibiting dynamin-mediated endocytosis[J]. PNAS, 2017, 114 (18): E3642-E3651

E-mailrenlili@njtech.edu.cn